Table of Contents

Original Article(continued)

1. In vitro Antioxidant Potential and Cytotoxicity Study of Asparagus aethiopicus L. Extracts on HT-29 Human Colon Cancer Cell Line

   Suhas Suresh Awati, Ritu M Gilhotra, Santosh K Singh, Vinit Raj, Kiran A Wadkar

   pp. s570-s579 · DOI: 10.5530/ijper.54.3s.156 · 2020

   Objectives: To decide the phytochemical constituents, antioxidant and anticancer potential of Asparagus aethiopicus L. extracts on HT-29 human colon malignant growth cell line. Methods: The roots of plant were exposed to…

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2. Clot Lysis Capacity of Andrographis paniculata and its Pure Compound Andrographolide

   Muhammad Torequl Islam

   pp. s580-s585 · DOI: 10.5530/ijper.54.3s.157 · 2020

   Background: Andrographis paniculata and its main components andrographolide (AGL) have been reported for their promising cardio-protective effects in experimental animals. Aim: To investigate clot lysis activity of A. pa…

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3. HPTLC Densitometric Quantification of Kaempferol from Leaves of Euphorbia neriifolia

   Prashant Y. Mali, Swapnil Goyal

   pp. s586-s592 · DOI: 10.5530/ijper.54.3s.158 · 2020

   Objectives: To study HPTLC densitometric quantification of kaempferol in aqueous extract fraction (EN6) of leaves of Euphorbia neriifolia Linn. Methods: Chromatographic method was employed on pre-washed and pre-activated…

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4. Phytoformulation of Tagetes patula for Improving Permeability and Prevention of Hyperlipidaemia

   Sneha Nawale, Sujit Das, Priyanka N, Ganga Raju M

   pp. s593-s600 · DOI: 10.5530/ijper.54.3s.159 · 2020

   The present study was aimed to formulate phytoformulation of Tagetes patula (MSTP) and its evaluation for antihyperlipidemic activity with triton X-100 and propyl thiouracil induced hyperlipidaemia models. Microsuspensio…

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5. Anti-diarrheal Activity of Caffeine: A Modulatory Effect with Loperamide and through 6FH5 (PIK3CG) Protein Interaction Pathway

   Farhana Faria, Shardar Mohammad Hafiz Hassan, Rajib Hossain, Mahmuda Akter Mukta, Md. Ashiqur Rahman Chowdhury, Muhammad Torequl Islam

   pp. s601-s609 · DOI: 10.5530/ijper.54.3s.160 · 2020

   Background: Caffeine (CAF) is known for its central nervous system stimulatory effect. Although, CAF use in diarrhea, especially in Runner's diarrhea is still controversial, but it has been reported that dark tea contain…

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6. Synthesis and QSAR Studies of Novel Pyrazoline Derivatives as Antiproliferative Agent

   Prafulla Madhukarrao Sable, Nusrat Bhuru Ali Sayyad

   pp. s610-s619 · DOI: 10.5530/ijper.54.3s.161 · 2020

   Background: Regardless of recent advances in the biological processes leading to the development of cancer, there is still a need for new and effective agents to help bring this disease under control. The revelation of t…

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7. In silico Docking and 3D-QSAR Studies of Novel N’-substituted-(pyrrolyl-phenoxy) Acetohydrazides as Enoyl-ACP Reductase Antagonists

   Shrinivas Dattatraya Joshi, SR Prem Kumar, Venkatarao H Kulkarni, Ali Mohamed Alshabi, Ibrahim Ahmed Shaikh, TM Aminabhavi

   pp. s620-s632 · DOI: 10.5530/ijper.54.3s.162 · 2020

   In search of potent anti-mycobacterial agents, enoyl-ACP reductase enzyme found to be most probable due to its imperative role in type II fatty acid synthesis (FAS), while mycolic acid production in Mycobacterium tubercu…

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8. Synthesis and Characterization of Some Novel N-Phenylpyrazole Analogues for the Evaluation of their Potentials as Anticancer, Antimicrobial and Antioxidant Agents

   Vijai Varma Pothuri, Venkata Satya Machiraju Palagummi, Samba Siva Rao Vasa

   pp. s633-s643 · DOI: 10.5530/ijper.54.3s.163 · 2020

   Objectives: With a view to invent new anticancer agents, the authors proposed to prepare a series of N-phenylpyrazole derivatives by introducing biologically active pharmacophores viz., Fluoro/Fluoromehtyl benzamide and …

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9. A Novel Validated Stability Indicating Analytical Method for Simultaneous Quantification of Metformin Hydrochloride and Empagliflozin in Bulk and Marketed Formulation by HPTLC using Box-Wilson Experimental Design Approach

   Manojkumar K. Munde, Nilesh S. Kulkarni, Ashim K. Sen, Dhanya B. Sen

   pp. s644-s656 · DOI: 10.5530/ijper.54.3s.164 · 2020

   Background: A novel stability indicating analytical method was developed and validated by High Performance Thin Layer Chromatography (HPTLC) using Design of experiment approach. The proposed method is useful for quantifi…

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10. Application of Design of Experiment Based Innovative Approach in Method Development and Validation of RP-HPLC for Estimation of Azilsartan in Bulk and Pharmaceutical Tablet Dosage Form

    Siddhata Arjun Deshmukh, Suvarna Sharad Vanjari, Rajendra Bhagwan Patil, Kishanchandra Radheshyam Khandelwal

    pp. s657-s666 · DOI: 10.5530/ijper.54.3s.165 · 2020

    Aim: Azilsartan is an angiotensin II receptor blocker used in the treatment of hypertension. Using the DoE based approach in reversed-phase high-performance chromatography method was developed and validated as per ICH gu…

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11. Novel Validated UV Spectroscopic Method for Routine Analysis of Decitabine Drug Substance

    Ankit Awasthi, Dheeraj HM, Muddukrishna Badamane Sathyanarayana

    pp. s667-s670 · DOI: 10.5530/ijper.54.3s.166 · 2020

    Objectives: In the proposed study, a basic, novel, protected economic, delicate and cost-effective UV-Spectrophotometric technique for the analysis of Decitabine which is antineoplastic drug. Methods: The created method …

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12. Method Development and Validation of Ephedrine and Pseudoephedrine in Horse Urine by Liquid Chromatography-Tandem Mass Spectrometry

    Ashok Kumar Maurya, Puran Lal Sahu, Sakshi Jethi, Himank Gosain, Kapendra Sahu

    pp. s671-s676 · DOI: 10.5530/ijper.54.3s.167 · 2020

    Background: A comprehensive, fast and precise method for the quantification of ephedrine and pseudoephedrine in horse urine was established and validated utilizing Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS…

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13. A Validated Stability-indicating RP-HPLC Method for Piperine Estimation in Black Pepper, Marketed Formulation and Nanoparticles

    Bhaskar Kurangi, Sunil Jalalpure

    pp. s677-s686 · DOI: 10.5530/ijper.54.3s.168 · 2020

    Aim: The aim of the study was to develop and validate a simple stability indicating reversephase High Performance Liquid Chromatography (RP-HPLC) method for quantitative analysis of piperine in Ayurvedic marketed formula…

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14. Simultaneous Quantification of Quercetin and Syringic Acid in Methanolic Extract of Leucas lavandulifolia by using Validated HPTLCDensitometric Method

    Pushpendra Kumar Shukla, Akanksha Srivastava, Ankita Misra, Sharad Srivastava

    pp. s687-s694 · DOI: 10.5530/ijper.54.3s.169 · 2020

    A simple, sensitive and reliable High Performance Thin Layer Chromatography (HPTLC) method was developed for the simultaneous quantification of bioactive compounds i.e quercetin and syringic acid in Leucas lavandulifolia…

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15. Impact of Verbal and Web-based Patient Education Programs Driven by Clinical Pharmacist on the Adherence and Illness Perception of Hypertensive Patients

    Zekiye Yılmaz, Mesut Sancar, Betül Okuyan, Osman Yeşildağ, Fikret Vehbiİzzettin

    pp. s695-s704 · DOI: 10.5530/ijper.54.3s.170 · 2020

    Background: Patient education is a substantial factor for the management of inveterate diseases. The aim of this study is to assess the impact of patient education given by clinical pharmacist using different (verbal and…

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16. Machine Learning-Based Decision Support System for Early Detection of Breast Cancer

    Mochen Li, Gaurav Nanda, Santosh Chhajedss, Raji Sundararajan

    pp. s705-s715 · DOI: 10.5530/ijper.54.3s.171 · 2020

    Background: Breast cancer is one of the leading causes of death of women in the United States and also one of the most malignant cancer among women worldwide. Early, more accurate detection of breast cancer enables exten…

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17. Assessment of Knowledge of Diabetic Patients about Glycemic Abnormalities and Medicine Storage in Makkah during Hajj Pilgrimage

    Kolthoom Othman, Aejaz Abdul Latif Khan, Syed Mohammad Shakeel Iqubal, Tasneem Mohammed, Muazzam Sheriff Maqbul, Mohammed Gamal, Mohammad Mahmoud Al-Sanea, Mohammed Elmowafy, Khaled Shalaby, Dibya Sundar Panda, Saleh Alghamdi

    pp. s716-s721 · DOI: 10.5530/ijper.54.3s.172 · 2020

    Objectives: The main objective of this research was to evaluate the awareness about symptoms of diabetes and dealing with those symptoms, management and storage of drug especially for the heat sensitive hormone (insulin)…

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