Table of Contents

Nirmal Singh, Lalit Sharma

pp. 334-341 · DOI: 10.5530/ijper.52.3.39 · 2018

The enantiopure drugs are essential for disease treatment as the human body is amazingly chiral selective. Nearly 50% of drugs are chiral but the pharmacological activity resides with only one isomer, termed as eutomer, …

Azzurra Stefanucci, Adriano Mollica

pp. 342-350 · DOI: 10.5530/ijper.52.3.40 · 2018

Objective: The classroom is an ideal environment to enhance the learning experience by the use of alternative media. In this paper we aimed to inspire a class discussion on the famous television series “Breaking bad”, wi…

Kaushik Mandal, Hemant Gupta

pp. 351-362 · DOI: 10.5530/ijper.52.3.41 · 2018

Perspective: One can observe the sea changes that have been taken place in the Indian pharmaceutical business environment. There are challenges for this section and which is possible to overcome by quality human resource…

Ashlesha Pravin Pandit, Pooja Dilip Waychal, Atul Shankarrao Sayare, Vinita Chandrakant Patole

pp. 363-373 · DOI: 10.5530/ijper.52.3.42 · 2018

Objective: Tamarind seed polysaccharide (TSP) modifying to carboxymethyl tamarind seed kernel polysaccharide (CMTSP) could be potential polymer over synthetic one to target colon diseases. Ibuprofen was loaded in CMTSP t…

Adimulapu Anilkumar, Talasila Eswara Gopala Krishna Murthy, Avula Prameela Rani

pp. 374-380 · DOI: 10.5530/ijper.52.3.43 · 2018

Introduction: Dipyridamole is an Anti-platelet agent exhibits release problems at higher pH of small intestine due to its pH dependent solubility and precipitation followed by interruption of drug release from dosage for…

Sahukari Ravi, Punabaka Jyothi, Rajya Lakshmi, Bhasha Shanmugam, Ganjikunta Venkata Subbaiah, Kesireddy Sathyavelu Reddy

pp. 381-388 · DOI: 10.5530/ijper.52.3.44 · 2018

PRR11 is a cell cycle regulator involved in pathogenesis of cancer. Therapeutically it has been identified as target to inhibit cancer growth. In this study, we employed in silico strategies for determining 3D structure …

Ige Pradum Pundlikrao, Gadgil Prajakta Pradip, Sonawane Raju Onkar

pp. 389-397 · DOI: 10.5530/ijper.52.3.45 · 2018

Ciprofloxacin HCl is a BCS class III drug with high solubility and low permeability. It is a second generation fluoroquinolone antibiotic used in the treatment of mild to moderate urinary and respiratory tract infections…

Pondugula Sudhakara Reddy, KV Ramana Murthy

pp. 398-407 · DOI: 10.5530/ijper.52.3.46 · 2018

Introduction: The objective of the present formulation research is to deliver the drugs at a faster rate and to provide immediate onset of action in a shorter period of time with improved bioavailability. Materials and M…

Shaikh Karimunnisa, Pandhe Puja, Kale Sangita, Bothiraja Chellampillai

pp. 408-415 · DOI: 10.5530/ijper.52.3.47 · 2018

Introduction: The main objective of the present study was to develop and evaluate long circulating pegylated niosomal formulation of albendazole (ABZ). It was hypothesized thatpegylated niosomes would increase the system…

Ayşe Baldemir, Ülkü Karaman, Selen İlgün, Gamze Kaçmaz, Betül Demirci

pp. 416-425 · DOI: 10.5530/ijper.52.3.48 · 2018

Background: Artemisia ludoviciana Nutt. (Asteraceae) is an aromatic, herbaceous, perennial plant and known commonly name as “White Sage”, “Black Sage”, “Prairie Sage” or “Cudweed Sagewort”. It is traditionally used as an…

Basavaraj Mrutyunjay Dinnimath, Sunil Satyappa Jalalpure

pp. 426-436 · DOI: 10.5530/ijper.52.3.49 · 2018

Background: Aerva lanata (L) Juss. Ex. Schult. (Amaranthaceae) commonly known as Pashanabheda is used traditionally in Indian system of medicines for various diseases including urolithiasis. Objective: Screening of bioac…

Mustafa Sevindik, Hasan Akgul, Celal Bal, Zeliha Selamoglu

pp. 437-441 · DOI: 10.5530/ijper.52.3.50 · 2018

Introduction: Mushroom species have been used for medical purposes and as nutrients since the old times. The present study aimed to determine phenolic content, antioxidant activity and heavy metal content of Cyclocybe cy…

Mohammed I Sakran, Haddad A El Rabey, Yaaser Q Almulaiky, Mohammed A Al-Duais, Mohamed Elbakry, Uzma Faridi

pp. 442-448 · DOI: 10.5530/ijper.52.3.51 · 2018

Objective: the present research was focused to evaluate the date palm resistance to osmotic stress exerted by three concentrations of poly ethylene glycol 6000 in three months seedlings as reflected by the change in phen…

Deepika Sharma, Nutan Thakur, Jitendraa Vashistt, Gopal Singh Bisht

pp. 449-455 · DOI: 10.5530/ijper.52.3.52 · 2018

Objectives: Nanoparticles synthesis via green approach is a scorching theme of research nowadays as it minimizes the use of harmful chemicals. Not much work has been done on bio reduction of copper salts; therefore our p…

Emine Nakilcioğlu-Taş

pp. 456-466 · DOI: 10.5530/ijper.52.3.53 · 2018

Introduction: Coffee is one of the most widely consumed beverages by the people all around the world. This study was aimed to evaluate the effect of sugar addition, double effects of sugar addition and roasting degree on…

Medhi Arundhati, Chetia Dipak, Rudrapal Mithun

pp. 472-479 · DOI: 10.5530/ijper.52.3.55 · 2018

Introduction: The emergence of multi-drug resistant strains of Plasmodium falciparum has increasingly become a serious health problem worldwide. To address this challenging issue, there is an urgent need to discover and …

Afroze Alam, Vinay Pandit, Shailendra Kumar, Kamlesh Kumar Naik, Mahfoozur Rahman, Mohan Lal Verma

pp. 480-491 · DOI: 10.5530/ijper.52.3.56 · 2018

Objectives: The aim of the study is to develop new synthetic anti-leishmanial agents as flavanone analogues, which should have low toxicity with noticeable yield. Methodology: The starting materials for the synthesis of …

Suresh Palamadai Krishnan, Kaustubh Sunil Hiray, Siddhant Vyas

pp. 492-504 · DOI: 10.5530/ijper.52.3.57 · 2018

The in vitro in silico experimental flow (multi- spectroscopy and docking) demonstrated the binding of Luteolin and Quercetin separately with Bovine Serum Albumin. For the first time, we are reporting the relative UV-vis…

Chunyan Liu, Min Bian, Lijun Yu, Chengxi Wei

pp. 505-513 · DOI: 10.5530/ijper.52.3.58 · 2018

Context: Aims: In order to search new compounds with higher anti-inflammatory activities and lower toxicity. 1,2,3-triazole and 1,2,4-triazole derivatives were designed and synthesized, and then the anti-inflammatory act…

Rohini Kanagavelu, Shinny Sunny, Preethi Balasundaram, Ramanathan Karuppasamy, Shanthi Veerappapillai

pp. 514-524 · DOI: 10.5530/ijper.52.3.59 · 2018

M2 protein, a crucial glycoprotein present on the viral envelope of Influenza A virus plays an important role in the replication and budding of influenza A virus in the host organism. Due to its primal role in the life c…