Table of Contents

Original Article

1. Solid Dispersion as a Technical Solution to Boost the Dissolution Rate and Bioavailability of Poorly Water-Soluble Drugs

   Mohamed Salah Attia, Azza Ali Hasan, Fakhr-Eldin Soliman Ghazy, Eman Gomaa

   pp. s327-s339 · DOI: 10.5530/ijper.55.2s.103 · 2021

   Solid dispersion (SD) is one of the oldest and widely utilized techniques to improve the solubility of slowly dissolving drugs. A variety of pharmaceutically compatible additives using different emerging technology is us…

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2. Prescription: A Situation Analysis in Indian Health Care System

   Sathish Venkatasamy Dhayalan, Arulkumaran G, Shalini Sivadasan

   pp. s340-s344 · DOI: 10.5530/ijper.55.2s.104 · 2021

   A prescription is the vital written communication from physician to patient, which consist of instruction to pharmacist on dispensing of drug regimen. Prescription writing is a critical task that suggests prescriber’s re…

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3. Impact of International Accreditation in Pharmacy Education: Pharmacy School Students’ Perspective

   Rula Darwish, Mohammad Saleh, Khawlah Ammar, Mohammad AlMasri

   pp. s364-s372 · DOI: 10.5530/ijper.55.2s.107 · 2021

   Background: The accreditation of undergraduate Pharmacy Schools is an important quality assurance process. In spite of the widespread adoption of international accreditation processes and an increasing attention on accre…

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4. Transformation of Teachers to Mentors: Prerequisite of Time is to Excel Innovative Practices in Academics

   Neelesh Malviya, Sapna Malviya, Rajiv Saxena, Manisha Dhere

   pp. s373-s378 · DOI: 10.5530/ijper.55.2s.108 · 2021

   The perception of Mentoring is definitely not new; indeed, it comes from a character named “Mentor” in Homer’s Odyssey. He was a trusted mentor to Odysseus’ son. The recent studies and Figures have given rise to prospero…

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5. Role of Learning Approach in Determining Learning Outcome During Active and Passive Learning Sessions in Pharmacology

   Vimala Ananthy, Suresh Narayanan, Arthi Asokan

   pp. s379-s384 · DOI: 10.5530/ijper.55.2s.109 · 2021

   Objectives: The objective of the study is to estimate the difference in knowledge gain between the students of varied learning approaches during didactic lectures and concept mapping lectures. Materials and Methods: The …

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6. Preparation and Characterization of Chitosan Silicate Conjugate: It’s Role as a Super Disintegrant in Orally Fast Dissolving Films

   Satheesha Babu Birur Kotappa, Podamala Rama Smriti

   pp. s385-s395 · DOI: 10.5530/ijper.55.2s.110 · 2021

   Aim: The aims of the present research work was to prepare and characterize the chitosan silicate conjugate, conjugate was included in orally fast dissolving films of levo cetirizine di hydrochloride as a super disintegra…

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7. Datura stramonium Leaves Mucilage Aided Buccoadhesive Films of Aceclofenac using 32 Factorial Design with Design-Expert Software

   Hindustan Abdul Ahad, Haranath Chinthaginjala, Manchikanti Sai Priyanka, Dasari Rahul Raghav, Madana Gowthami, Varam Naga Jyothi

   pp. s396-s404 · DOI: 10.5530/ijper.55.2s.111 · 2021

   Aim and Objectives: The main motto of this work was to search the additive effect of Datura stramonium leaves mucilage in the making of buccoadhesive film by taking Aceclofenac as a model drug. Materials and Methods: Nin…

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8. Solubility Enhancement of Embelin by Complexation with Beta Cyclodextrin

   Jashna K Kani, Elizabeth N Xavier

   pp. s405-s413 · DOI: 10.5530/ijper.55.2s.112 · 2021

   Introduction: Embelin, a phytoconstituent obtained from Embelia ribes of the Myrsinaceae family, has anti-cancer, anti-inflammatory, anti-bacterial, anti-fertility, analgesic, antidiabetic, anti-depressant and wound heal…

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9. Development of Colon Targeting Tablet of a JAK Inhibitor to Combat Chronic Ulcerative Colitis: A Novel Approach for Local Drug Delivery

   Vakar Vakar, Rupa Mazumder, Swarupanjali Padhi, Kirpa Shanker Tiwari, Parikh Kinjal

   pp. 414-s427 · DOI: 10.5530/ijper.55.2s.113 · 2021

   Background: Tofacitinib, a pan-Janus kinase (JAK) inhibitor, initially used for the treatment of rheumatoid arthritis, was later found to have robust efficacy in Phase 2 and Phase 3 ulcerative colitis clinical trials. It…

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10. Curcumin Loaded Eudragit S100/PLGA Nanoparticles in Treatment of Colon Cancer: Formulation, Optimization, and in-vitro Cytotoxicity Study

    Apeksha Saraf, Nidhi Dubey, Nitin Dubey, Mayank Sharma

    pp. s428-s440 · DOI: 10.5530/ijper.55.2s.114 · 2021

    Introduction: Polymeric nanoparticles provide a promising strategy for site-specific delivery of dietary phytochemicals in the treatment of colon cancer. Curcumin (CU) is a dietary phytochemical with well-proven anti-can…

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11. Polyacrylamide Grafted Gum Acacia (GA-g-PAM) Graft Copolymer as Efficient Polymeric Scaffold

    Trishna Bal, Priyashi Singh, Aditya Dev Rajora, Sandeep Garg, Barnali Dasgupta Ghosh, Ashok Kumar Pattnaik

    pp. s441-s447 · DOI: 10.5530/ijper.55.2s.115 · 2021

    Background: Natural polysaccharides are mostly not stable in their original form but their biodegradable properties can be beneficial for use as polymeric scaffolds for tissue engineering. Microwave irradiation assisted …

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12. Proof-of-concept for Site-specific Delivery of Mesalamine Nanoparticles for Effective Therapy in Colitis

    Nagaraja Sreeharsha, Rashmi Narayan, Joshi Vijaya, Anroop Nair

    pp. s448-s456 · DOI: 10.5530/ijper.55.2s.116 · 2021

    Background: Mesalamine loaded polymeric nanoparticles were prepared using three different polymers namely, Eudragit RS100, PLGA (50:50), or Eudragit RLPO, with an aim of targeted delivery to the inflamed colon. Materials…

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13. Protective Role of Caffeic Acid in Cognitive Dysfunction and Oxidative Stress Induced by Colchicine in Rats

    Surubhotla Raviteja, Suman Manandhar, Keerthi Priya, Gangadhar Hari, K Sreedhara Ranganath Pai

    pp. s457-s467 · DOI: 10.5530/ijper.55.2s.117 · 2021

    Purpose: Alzheimer’s is a disease affecting mostly the Older population leading to the deterioration of cognitive capabilities. The protective effect of Caffeic acid in Colchicine-induced dementia was evaluated in the cu…

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14. Embelin and Levodopa Combination Therapy Mitigates Parkinson's Disease Complications in Mice

    Anand Koppal, Senthilkumar Sivanesan, Vagdevi Hangarakatte Ramachandra, Ethirajan Sukumar, Rajagopalan Vijayaraghavan

    pp. s468-s478 · DOI: 10.5530/ijper.55.2s.118 · 2021

    Purpose: The present work evaluated the neuroprotective potential of embelin either alone and in combination with Levodopa in rotenone induced PD (Parkinson’s disease) model mice. Methods: Swiss albino male adult mice we…

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15. Effect of β-sitosterol on Insulin Receptor, Glucose Transporter 4 Protein Expression and Glucose Oxidation in the Gastrocnemius Muscle of High Fat Diet Induced Type -2 Diabetic Experimental Rats

    Madhan Krishnan, Shyamaladevi Babu, Ponnulakshmi Rajagopal, Sohara Parveen Nazar, Mayilvanan Chinnaiyan, Selvaraj Jayaraman

    pp. s479-s491 · DOI: 10.5530/ijper.55.2s.119 · 2021

    Background: The newly available medications are ineffective because of their unintended side effects in the treatment of type 2 diabetes. Hence, search drugs, from plant sources. β-sitosterol is plant sterols with struct…

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16. An Agro-ecological Zoning Model Highlighting Potential Growing Areas for Medicinal Plants in Punjab

    Preet Amol Singh, Anil Sood, Ashish Baldi

    pp. s492-s500 · DOI: 10.5530/ijper.55.2s.120 · 2021

    Background: The Ministry of AYUSH, Government of India has decided to emerge cultivation of medicinal plants as an attractive farming option due to a sharp increase in demand for medicinal plants. Punjab produces approxi…

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17. Evaluation of Antioxidant, Immunomodulatory and Anticancer Properties of Methanolic Extract of Neolamarckia cadamba Linn. Fruits

    Amrita Chatterjee, Neelima Sharma, Papiya Mitra Mazumder

    pp. s501-s509 · DOI: 10.5530/ijper.55.2s.121 · 2021

    Background: The immune system plays an important role in various diseased conditions. Patients with compromised immune function are at increased risk of exposure. Thus, the evaluation of immunomodulatory activity of plan…

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18. Green-synthesis of Silver Nanoparticles by Hygrophila auriculata Extract: Innovative Technique and Comprehensive Evaluation

    Smita Nayak, Priyanka Ghugare, Bhaskar Vaidhun

    pp. s510-s517 · DOI: 10.5530/ijper.55.2s.122 · 2021

    Background: Metal nanoparticles are of great scientific interest as they bridge the gap between the bulk and atomic structures. A number of methods of synthesizing nanoparticles have been developed and can be grouped int…

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19. The Anti-inflammatory Effect of Ethanol Extract Gel of Fig Leaves (Ficus carica Linn.) and Sidr Leaves (Ziziphus mauritiana Linn.)

    Muhammad Fariez Kurniawan, Ariffadli Prakoso, Muhammad Indra Irawan

    pp. s518-s527 · DOI: 10.5530/ijper.55.2s.123 · 2021

    Inflammation is a form of the body's response to tissue damage with a sign of epidermal thickness, an increase in the number of inflammatory cells and the expression of the COX-2 enzyme. The fig leaves and sidr dry leave…

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20. Neuroprotective Effect of Petroleum Ether, Methanolic and Aqueous Extracts of Fruits of Benincasa hispida on Lipofuscinogenesis and Fluorescence Product in Brain of D-galactose Induced Aging Accelerated Mice

    Digambar Balkrishna Ambikar, Guru Prasad Mohanta

    pp. s528-s534 · DOI: 10.5530/ijper.55.2s.124 · 2021

    Background: Aging is one of the major factors of development of neurodegenerative disorder and also involved in gradual learning and memory loss. In recent years discovery of antiaging drugs is one of the important topic…

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