Table of Contents

Original Article(continued)

1. Evaluation of in vitro Anti-cancer Activity of Linum usitatissimum and Mentha spicata Combination Extract against MCF7 Breast Cancer Cell-line

   Ashwini T, Glory Josephine I, Arul Amutha Elizabeth

   pp. s212-s216 · DOI: 10.5530/ijper.58.1s.21 · 2024

   Background/Aim: Breast cancer is one of the most common cancers among women in India. Though the current treatment is beneficial, it is complicated with lots of risks and disadvantages. So, the search for alternatives es…

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2. High-Performance Liquid Chromatography Method Development and Validation for Estimation of Mahanimbine in Curry Leaves

   Kanchan Nikam, Sachin Bhusari, Pravin Wakte

   pp. s217-s223 · DOI: 10.5530/ijper.58.1s.22 · 2024

   Aim: A designed, improved, and validated isocratic High Performance Liquid Chromatography method was used to study mahanimbine. Background: The method is evaluated for linearity, range, system applicability, LOD, LOQ, ac…

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3. Bio-analytical Method Development for Pharmacokinetic Study of Novel Lafutidine Formulation in Rabbit Plasma Using RP-HPLC

   Shanti Sagar, Lankalapalli Srinivas

   pp. s224-s231 · DOI: 10.5530/ijper.58.1s.23 · 2024

   Objectives: The main objective of the study is to carry out comparative in vivo pharmacokinetic study of novel formulation with marketed formulation of lafutidine using HPLC method. Materials and Methods: The animals wer…

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4. Development and Validation of Stability-indicating HPLC Method for Estimation of Azilsartan in Pharmaceutical and Solid Lipid Nanoparticles

   Neha Sanjay Bhasagi, Bhaskar Kallappa Kurangi, Vishal Arvind Mane, Swapnil Pandurang Patil, Moazzim Mainoddin Soudagar, Supriya Suresh Chimgave

   pp. s232-s240 · DOI: 10.5530/ijper.58.1s.24 · 2024

   Introduction: Azilsartan has been scientifically proven to be effective in treating hypertension. According to International Conference on Harmonization, the HPLC method was developed and validated to estimate the azilsa…

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5. Association and Prevalence of Alcoholism in Epileptic Patients at Tertiary Care Teaching Hospital

   Saurav Raj, Megha Hegde, Anupama Harigal, Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Viswanatha Swamy

   pp. s241-s244 · DOI: 10.5530/ijper.58.1s.25 · 2024

   Background: The effects of alcohol are complexly interlinked with the pathophysiology of epilepsy. Given that both epilepsy and alcohol have a significant detrimental impact on the brain; it is essential to investigate a…

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6. Evaluation of Prescriptions among Geriatric Patients Using Beer’s Criteria in a Tertiary Care Setting

   Fathima Nashiya, Hina Aisha, Chithrakshi Sapalya, Melwin Varghese, Sajan Francis P, Archana Bhat

   pp. s245-s251 · DOI: 10.5530/ijper.58.1s.26 · 2024

   Introduction: The geriatric population is prone to physiologic changes, thus increasing the risk of medication-related problems. The use of potentially inappropriate medications is associated with profound medical and sa…

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7. Evaluation of the Anti-ulcer Activity of Curcumin and Linseed Oil in an NSAID-induced Gastric Ulcer Model in Rats

   Alveera Zubair Ansari, Gaurav Mahesh Doshi

   pp. s252-s261 · DOI: 10.5530/ijper.58.1s.27 · 2024

   Background: Peptic Ulcer Disease is characterized by acid-induced ulcers in the stomach and duodenum. Their denuded mucosa with the distortion which extends into the submucosa or muscularis propria distinguishes them. Th…

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8. In vitro and in vivo Wound Healing Potential of Plant Commiphora caudata

   Lavanya Athilli, Arumugam Balasubramaniam

   pp. s262-s273 · DOI: 10.5530/ijper.58.1s.28 · 2024

   Background: Commiphora caudata is commonly called hill mango, an incredibly available species of Commiphora, and belongs to Burseraceae. Commiphora caudata is commonly used in Ayurveda and Siddha medicines. Different par…

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9. Ethanolic Leaf Extract of Centella asiatica L. Possesses Nephroprotection in an Animal Model of Nephrotoxicity

   Bhagya Venkanna Rao, Ramya Halasinamardhodi Beera Heggade, Hrishikeshavan Hiremagalur Jagannath

   pp. s274-s281 · DOI: 10.5530/ijper.58.1s.29 · 2024

   Background: Nephrotoxicity is a significant adverse effect of gentamicin, which is thought to be related to reactive oxygen species in the kidney. The purpose of this study was to look at how gentamicin-induced nephrotox…

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10. Investigation of Memory Enhancing Activity of Combination Extracts of Bauhinia variegata and Madhuca longifolia Leaves against Colchicine: An Experimental Study and Biochemical Alterations in Mice

    Pragati Khare, Kamal Kishore, Dinesh Kumar Sharma, Noopur Khare

    pp. s282-s288 · DOI: 10.5530/ijper.58.1s.30 · 2024

    Objectives: To investigate the role of combination of Madhuca longifolia (ML) and Bauhinia variegata (BV) ethanolic leaf extracts against oxidative damage in Swiss Albino mice and colchicine induced cognitive dysfunction…

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11. Design Formulation and in vitro Evaluation of Gastroretentive Microspheres of Selegiline Hydrochloride for Parkinson’s Disease by Design Expert

    Raghavarapu Prasanthi, Balusu Haarika, Subramanian Selvamuthukumar

    pp. s289-s297 · DOI: 10.5530/ijper.58.1s.31 · 2024

    Introduction: Selegiline hydrochloride is primarily used to treat Parkinson’s disease. Selegiline hydrochloride mucoadhesive microspheres were prepared to improve the bioavailability of the drug and its appropriate thera…

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12. Secondary Metabolites and Antioxidants Activity from Citronella Grass Extract (Cymbopogon nardus L.)

    Rofiatun Solekha, Hery Purnobasuki, Ni Nyoman Tri Puspaningsih, Putri Ayu Ika Setiyowati

    pp. s298-s305 · DOI: 10.5530/ijper.58.1s.32 · 2024

    Background: Cymbopogon nardus L. is a rhizome plant that is widely used as traditional medicine. This research aimed to identify how the secondary metabolites of citronella grass including stems, leaves, and roots and ot…

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13. Enhancement of Solubility of Albendazole by Inclusion Complexation with Nanosponges and β-Cyclodextrin

    Monica Raghavendra Prasad Rao, Saloni A. Sakharwade

    pp. s306-s315 · DOI: 10.5530/ijper.58.1s.33 · 2024

    Aim: Objective of work was to compare role of β-Cyclodextrin (β-CD) and Nanosponges (NS) prepared with different cross-linking ratios and different drug loading ratios to enhance solubility and dissolution rate of Albend…

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14. Preparation, in vitro and in vivo Characteristics of Floating in situ Gel of Carvedilol Using Semi Synthetic and Natural Polymers to Enhance the Oral Bioavailability

    Ananthakumar Ramalingam, Sathesh Kumar Sukumaran, Chitra Krishnan

    pp. s316-s324 · DOI: 10.5530/ijper.58.1s.34 · 2024

    Background/Aim: The purpose of this study was to design and prepare floating in situ gel to sustain Carvedilol (CVD) release and enhance oral bioavailability. Various floating in situ gel formulations of the CVD were pre…

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15. Development and Validation of a Bioanalytical Method to Determine Empagliflozin in Human Plasma Using UPLC-MS/MS

    Mani Sumithra, David John Andrew, Muthukumar Vijey Aanandhi

    pp. s325-s331 · DOI: 10.5530/ijper.58.1s.35 · 2024

    Aim: The study we are conducting aims to establish a validated method for measuring empagliflozin in plasma using UPLC MS/MS. Materials and Methods: Sodium-Glucose co Transporter inhibitors (SGLTi), a novel class of diab…

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