Antimicrobial Activity and Chemical Composition Screening of Epilobium montanum Root

Indian Journal of Pharmaceutical Education and Research

  • Kerem Canli1Department of Biology, Faculty of Science, Dokuz Eylül University, Izmir, TURKEY.
  • Ali Yetgin2Department of Biotechnology, Institute of Engineering and Science, Izmir Institute of Technology, Izmir, TURKEY.
  • Ilgaz Akata3Department of Biology, Faculty of Science, Ankara University, Ankara, TURKEY.
  • Ergin Murat Altuner4Department of Biology, Faculty of Science and Arts, Kastamonu University, Kastamonu, TURKEY.

Volume 51 Issue 3s1 Pages s239-s243

DOI: 10.5530/ijper.51.3s.21

Abstract

Medical herbs have many bioactive component and they are used in microbial treatment since ancient time. The resistance of pathogen to antibiotic is became a critical problem, so novel antimicrobial agent related research is required. Epilobium montanum related antimicrobial research doesn't exist, therefore root of this medicinal plant investigation was applied against 17 bacteria and 1 fungi by using disk diffusion method. These microbial species include Bacillus, Enterobacter, Enterococcus, Escherichia, Klebsiella, Listeria, Pseudomonas, Salmonella, Staphylococcus and Candida genera. Besides, chemical composition of this sample was determined by Gas Chromatography-Mass Spectroscopy. The results were presented that E. montanum has antimicrobial activity against all tested microbial species except E. coli. Seventeen major chemical components were determined, but some composition of this sample is not match with library. For this reason, this medicinal plant contain unknown molecules and this molecules should be analysed by NMR spectra for 3D structure determination and identification.

Keywords

  • Epilobium montanum
  • Medicinal Plant
  • Antimicrobial Activity
  • Chemical
  • Composition
  • Disk Diffusion Method
  • GC-MS
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