Application of Bioapigyn® Herbal Ointment for the Treatment of Lower Genital Tract Infections

Abstract

Objective: The purpose of this work was development and testing of new herbal ointment for the treatment of lower genital tract infections in females. Material and Methods: 80 female patients with positive swabs to at least one microorganism (U. urealyticum, M. hominis, E. coli and Candida sp.) were randomly divided into three treatment groups. First group was treated 12 days (twice a day) with doxycycline antibiotic and 2 g of Bioapigyn vaginal ointment (once a day), second group with 2 g of ointment only and third group with antibiotic only (12 days; twice a day). Results: Following the therapy all the swabs were negative to M. hominis regardless of the treatment group. Eradication of U. urealyticum was 100%, 87% and 62% and E. coli 75%, 67% and 33% in antibiotic + herbal ointment, herbal ointment only and antibiotic only group, respectively. None of the patients in the first and second group developed antibiotic-associated candidiasis compared to 80% positive swabs in the antibiotic only group. Conclusion: Bioapigyn vaginal ointment has significant antimicrobial potential against common vaginal pathogens which is even better compared to standard antibiotic.