Adjunct Use of Pranic Healing Colours in Neuroprotection of SH-SY5Y Parkinson’s Disease Cell Models

Indian Journal of Pharmaceutical Education and Research

  • Nagendra Prasad Krishnamurthy1World Pranic Healing Foundation, India-Research Centre, Mysuru, Karnataka, INDIA.
  • Sanskruti Patil2Department of Pharmaceutical Biotechnology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, INDIA.
  • Vinu Vijayakumar1World Pranic Healing Foundation, India-Research Centre, Mysuru, Karnataka, INDIA.
  • Raghu Chandrashekar Hariharapura2Department of Pharmaceutical Biotechnology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, INDIA.
  • Srikanth Nagaraja Jois1World Pranic Healing Foundation, India-Research Centre, Mysuru, Karnataka, INDIA.

Volume 60 Issue 4s Pages s1650-s1656

DOI: 10.5530/ijper.20264546

Abstract

Background: Parkinson’s Disease (PD) involves dopaminergic neurodegeneration associated with mitochondrial dysfunction, oxidative stress, and apoptosis. Objectives: To evaluate the effects of Pranic Healing (PH) colour exposures on dopamine-induced cytotoxicity, Mitochondrial Membrane Potential (MMP), apoptosis, and oxidative stress in SH-SY5Y neuroblastoma cells. Materials and Methods: SH-SY5Y cells were exposed to rotenone to induce neurotoxicity and treated with dopamine followed by different PH colour therapies. Cell viability (MTT), MMP (Rhodamine-123), apoptosis (flow cytometry), and reactive oxygen species (ROS) were assessed. Data were analysed using inferential statistics followed by appropriate post hoc test. Results: All PH colour treatments combined with Levodopa significantly reduced cytotoxicity versus disease control. Colour Light Whitish Green-Light Whitish Violet showed the strongest cyto-protection (24.27% cytotoxicity). Colours Ordinary Violet and White markedly improved MMP beyond control levels, while Colours Light Whitish Violet and Light Whitish Green-Light Whitish Violet significantly reduced ROS, comparable to pharmacological control. Conclusion: PH colour exposure enhanced neuronal viability, mitochondrial function, and redox balance in a Parkinsonian cell model, suggesting potential complementary neuroprotective benefits.

Keywords

  • Biofield
  • Complementary Therapy
  • Neuroprotection
  • Prana
  • Yoga
IJOPP

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