Emerging Trends and Conceptual Mapping in Network Pharmacology Research: A Bibliometric Analysis (2008-2023) Using VOSviewer

Indian Journal of Pharmaceutical Education and Research

  • Siddig Ibrahim Abdelwahab1Health Research Center, Jazan University, Jazan, SAUDI ARABIA.
  • Manal Mohamed Elhassan Taha1Health Research Center, Jazan University, Jazan, SAUDI ARABIA.
  • Abdullah Farasani1Health Research Center, Jazan University, Jazan, SAUDI ARABIA., 2College of Nursing and Health Science, Jazan University, Jazan, SAUDI ARABIA.
  • Saleh M Abdullah2College of Nursing and Health Science, Jazan University, Jazan, SAUDI ARABIA.
  • Saeed Alshahrani3Department of Pharmacology and Toxicology, College of Pharmacy, Jazan University, SAUDI ARABIA.
  • Ahmad Assiri4Department of Dermatology, Faculty of Medicine, Jazan University, Jazan, SAUDI ARABIA.
  • Jobran M Moshi2College of Nursing and Health Science, Jazan University, Jazan, SAUDI ARABIA., 1Health Research Center, Jazan University, Jazan, SAUDI ARABIA.
  • Nizar A. Khamjan2College of Nursing and Health Science, Jazan University, Jazan, SAUDI ARABIA.
  • Humaid Al-shamsi5Burjeel Medical City, Abu Dhabi, P.O. Box 92510, UNITED ARAB EMIRATES., 6College of Medicine, Ras Al Khaimah Medical and Health Sciences University, Ras Al Khaimah, UNITED ARAB EMIRATES.
  • Abrar Fahad Alshahrani7Department of Clinical Nutrition, College of Nursing and Health Sciences, Jazan University, Jazan, SAUDI ARABIA.
  • Syam Mohan8School of Health Sciences, University of Petroleum and Energy Studies, Dehradun, Uttarakhand, INDIA., 9Center for Global Health Research, Saveetha Medical College, and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Kuthambakkam, Tamil Nadu, INDIA.

Volume 60 Issue 2s Pages s644-s655

DOI: 10.5530/ijper.20262593

Abstract

Background: Network Pharmacology (NP) aims to understand drug actions and their interactions with multiple targets using computational methods. Objectives: This provides a network-based approach to comprehensively investigating the effects of drugs on complex biological systems. The main objective of this bibliometric analysis in NP research (NPR) is to gain insight into the impact of research, emerging trends, collaborations, and the overall research landscape. Materials and Methods: The study retrieved data from the Scopus database and employed advanced bibliometric techniques, including citation analysis, co-occurrence mapping, and trend detection using VOSviewer software. The analysis examined the annual publication trends, authorship patterns, collaborations, and the emergence of key research themes in NPR. Results: A total of 6,134 articles were extracted. NPR exhibited steady growth. China is the most productive and collaborative country. Five clusters of research themes were derived: mechanisms of action and molecular mechanisms, Traditional Chinese Medicine (TCM) and herbal compounds, disease-specific research, inflammation and immune-related research, and validation and simulation. In NPR, molecular docking, apoptosis, the cell cycle, ulcerative colitis, and sepsis are trending topics. Conclusion: The study revealed an increase in the production of NPR and its conceptual structures. It lays the foundation for advancing knowledge of what has been published and possible areas for improvement in NPR

Keywords

  • Network pharmacology
  • Performance
  • Themes clustering
  • Bibliometrics
  • VOSviewer
IJOPP

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