A Comprehensive Review on Management of Insulin Resistance Disorder by Innovative Technologies and Advancement of Precision Medicinal Therapies

Indian Journal of Pharmaceutical Education and Research

  • Aman Shrivastava1Department of Pharmacology, College of Pharmacy, Institute of Professional Studies, Gwalior, Madhya Pradesh, INDIA.
  • Sumeet Dwivedi2Department of Pharmacognosy, Acropolis Institute of Pharmaceutical Education and Research, Indore, Madhya Pradesh, INDIA.
  • Shiv Narayan3Department of Pharmacology, Goel Institute of Pharmacy and Sciences, Lucknow, Uttar Pradesh, INDIA.
  • Abhishek Dwivedi4Department of Pharmacognosy, Dr. Satyendra Kumar Memorial College of Pharmacy, RKDF University Bhopal, Madhya Pradesh, INDIA.
  • Jailani Shiekmydeen5Department of Formulation R&D, Alpha Pharma, KAEC, Rabigh, SAUDI ARABIA.
  • Amit Anand6Department of Pharmacognosy JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru, Karnataka, INDIA.
  • Arvind Kumar Tripathi7Department of Biotechnology, A.P.S. University, Rewa, Madhya Pradesh, INDIA.
  • Kuldeep Singh8Department of Pharmacology, Institute of Pharmaceutical Research, GLA University, Mathura, Uttar Pradesh, INDIA.

Volume 59 Issue 3s Pages s814-s824

DOI: 10.5530/ijper.20250849

Abstract

The increasing prevalence of insulin resistance disorders, including type 2 diabetes and metabolic syndrome, underscores the urgent need for advanced diagnostic and therapeutic strategies. This review aims to explore the role of innovative precision medicine in revolutionizing the assessment and management of insulin resistance disorders. By integrating genetic, epigenetic and environmental data, precision medicine provides a more nuanced understanding of disease mechanisms and enables personalized treatment approaches. This review mainly highlights recent advancements in biomarker identification, novel therapeutic targets and individualized treatment regimens driven by precision medicine. We emphasize the importance of emerging technologies like genomics, metabolomics and digital health tools in enhancing diagnostic accuracy and therapeutic efficacy. The integration of these innovations promises to improve patient outcomes and offers a new paradigm in the management of insulin resistance disorders. By addressing the heterogeneous nature of insulin resistance disorders, precision medicine offers a promising avenue for more effective and efficient healthcare solutions. Despite the potential, challenges remain, including ethical considerations, high costs and the need for specialized training. The successful integration of precision medicine into routine clinical practice requires standardized protocols and improved infrastructure. Future research should address these challenges and focus on translating technological and scientific advancements into practical, equitable healthcare solutions. In conclusion, precision medicine offers a transformative approach to managing insulin resistance, with the potential to improve patient outcomes and advance our understanding of metabolic disorders

Keywords

  • Genomic Biomarkers
  • Healthcare Integration
  • Insulin Resistance
  • Metabolic Disorders
  • Targeted Therapies
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