Aquasome: As Drug Delivery Carrier in the Pharmaceutical Field

Indian Journal of Pharmaceutical Education and Research

  • Varsha Sahu1Department of Pharmaceutical Science, Utkal University Vani Vihar, Bhubaneswar, Odisha, INDIA.
  • Sunit Kumar Sahoo1Department of Pharmaceutical Science, Utkal University Vani Vihar, Bhubaneswar, Odisha, INDIA.
  • Amaresh Chandra Sahoo2Department of Pharmaceutics, Institute of Pharmacy and Technology, Salipur, Odisha, INDIA.

Volume 58 Issue 3s Pages s757-s767

DOI: 10.5530/ijper.58.3s.77

Abstract

In the pharmaceutical field, various diagnostic tools and delivery systems are available which used for the identification of diseases and treatment. Aquasome is a new type of vesicular drug delivery system. It is a self-assembled nanoparticle with a three-layered structure consisting of a nanocrystalline central core on top of that carbohydrate layer is present that adsorbs the bio-actives or drugs on that layer. A carbohydrate coating protects and preserves the structural integrity of the bioactive. Aquasome has great potential because of its properties. It acts as a carrier for various therapeutic drugs and bioactive materials. This review provides information about aquasome, their historical development, the importance of carbohydrates, their properties, advantages, disadvantages, limitations, characterization techniques, applications, route of administration, patents, marketed products, consequences, challenges, and prospects. Therefore, researchers will benefit from this review, about aquasome, their applications and prospective in pharmaceutical science.

Keywords

  • Aquasome
  • Vesicular
  • Nanocrystalline
  • Three-layered
  • Self-assembly
  • Structural integrity
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