An Overview on the Insulin Preparations and Devices

Indian Journal of Pharmaceutical Education and Research

  • Shery Jacob1Department of Pharmaceutics, College of Pharmacy, Gulf Medical University, Ajman, UAE.
  • Mohamed Aly Morsy2Department of Pharmacology, Faculty of Medicine, Minia University, El-Minia, EGYPT.,
  • Anroop Nair3Department of Pharmaceutics, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, SAUDI ARABIA.

Volume 52 Issue 4 Pages 550-557

DOI: 10.5530/ijper.52.4.64

Abstract

Insulin preparations are the mainstay in the management of type 1 along with various type 2 diabetes. Available insulin preparations are either short-acting or long-acting or mixture to mimic the physiological insulin secretion and their doses need to be individualized. Attempting to imitate normal secretion of insulin can be valuable paradigm for understanding and providing effective therapy. This review provides an outline about the composition, use, route of administration, injection site, pharmacokinetics, storage and handling of various insulin preparations. The efficacy and safety of various insulin preparations for the management of diabetes mellitus are discussed. In addition, the use and application of various insulin devices to improve adherence and provide optimum delivery are elaborated. Indeed, the patient awareness and adherence on these issues is crucial to achieve good glycemic control.

Keywords

  • Short-acting insulin
  • Long-acting insulin
  • Mixture
  • Analogues
  • Handling
  • Devices
  • Diabetes
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