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Published on:July 2017
Indian Journal of Pharmaceutical Education and Research, 2017; 51(4):672-678
Original Article | doi:10.5530/ijper.51.4.99

Biological Activities of Black Garlic Fermented with Lactobacillus plantarum PN05 and Some Kinds of Black Garlic Presenting Inside Vietnam


Authors and affiliation (s):

Nguyen Ngan, Mac Giang, Nguyen Tu*

School of Biotechnology, Hochiminh City International University, Vietnam National University - HOCHIMINH CITY, Quarter 6, Linh Trung Ward, Thu Duc District, Hochiminh City, VIETNAM.

Abstract:

Background: Black garlic has become more popular in Vietnam due to its interesting biological activities. Purpose: The quality of different black garlic preparations should be checked. Methods: 1010 colony forming units (CFUs) of Lactobacillus plantarum PN05 were mixed with 1 kg fresh garlic and then let turn into black garlic. The aqueous extract of this preparation and other black garlic products marketed in Vietnam were evaluated on antimicrobial, anticancer cell line activities and toxicity by using well agar diffusion, sulforhodamine B (SRB) assay and tissue observation respectively. Results: The tested black garlic extracts showed significant differences in the antimicrobial activities against Salmonella and Listeria monocytogenes. Moreover, different kinds of black garlic extracts showed different effects against human liver cancer cell line (HepG2). Surprisingly, higher amount of black garlic extracts showed the lower anti-HepG2 activity in some samples except extract of black garlic fermented with Lactobacillus plantarum PN05. However, mice used black garlic extracts could give the spleen to be larger significantly than control mice. Conclusion: The study warned human to be careful when using black garlic without any check. Key words: Black Garlic, Lactobacillus plantarum Pn05, Antimicrobial Activity, Anticancer Activity, Spleen Toxicity.

Key words: Black Garlic, Lactobacillus plantarum Pn05, Antimicrobial Activity, Anticancer Activity, Spleen Toxicity.

 

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The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmaceutical Education and Research (IJPER) [ISSN-0019-5464] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 1967.

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IJPER uses reference linking service using Digital Object Identifiers (DOI) by Crossref. Articles from the year 2013 are being assigned DOIs for its permanent URLs