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Published on:July 2017
Indian Journal of Pharmaceutical Education and Research, 2017; 51(4):679-683
Original Article | doi:10.5530/ijper.51.4.100

Formulation of an Emulgel Containing Strawberry Fruit Extract and in-vivo Evaluation for Different Skin Parameter


Authors and affiliation (s):

Rizwana Kausar*, Naveed Akhtar

Department of Pharmacy, Faculty of Pharmacy and Alternative Medicine, TheIslamia University of Bahawalpur, 63100, PAKISTAN.

Abstract:

Introduction: It has been indicated from previous research that strawberry consumption may be beneficial to improve skin appearance and its extract has antioxidant and antiinflammatory effects. Objective: The aim of present study was to fabricate an emulgel containing extract of strawberry (4%) and in-vivo evaluation on different skin parameters versus its base taken as control. Methods: Strawberry fruit extract, which was obtained by concentrating methanolic extract of strawberry fruit, was entrapped in the inner oily phase of (o/w) emulsion and then incorporated this emulsion into gel to develop emulgel. Both base (without extract) and active formulation were stored at different accelerated conditions for a period of six weeks to predict their stability. For in-vivo evaluation, both formulations were applied to the cheeks of healthy female human volunteers (n=13) for twelve weeks and various skin parameters were evaluated to measure any effect on skin produced by base and active formulations.The instrumental measurements were carried out with controlled temperature (18-20.6C°) and relative humidity (55- 65%). Results: Skin melanin, erythema and sebum showed a significant (decrease by active formulation. A significant (increase in skin moisture content was found by active formulation. Conclusion: Strawberry emulgel can be used to improve texture of skin and enhance whiting effect without causing any skin irritation.

Key words: Strawberry, Emulgel, Stability, Melanin, Sebum, Erythema.

 

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The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmaceutical Education and Research (IJPER) [ISSN-0019-5464] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 1967.

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IJPER uses reference linking service using Digital Object Identifiers (DOI) by Crossref. Articles from the year 2013 are being assigned DOIs for its permanent URLs