Published on:11th Feb, 2015
Indian Journal of Pharmaceutical Research and Education, 2011; 45(1):83-85
Pharmaceutical Education | doi:Nill
Indian Journal of Pharmaceutical Research and Education, 2011; 45(1):83-85
Pharmaceutical Education | doi:Nill
In-vitro Anthelmintic Activity of Rhizomes of Valeriana wallichii DC (Valerianaceae) Against Pheretima posthuma.
Abstract:
The development of anthelmintic resistance and high cost of convential anthelmintic drugs are the two major problems of helminthiasis treatment. This led to the evaluation of medicinal plants as an alternative source of anthelmintic. In the present study different extracts of rhizomes of Valeriana wallichi DC (Valerianaceae), at different concentrations (10-50mg/ml) were evaluated for their in vitro anthelmintic activity against adult Indian earthworms, Pheretima posthuma (Pheritimidae). The anthelmintic assay involved determination of time of paralysis and time of death of worms. Piperazine citrate (10mg/ml) was used as standard reference and distilled water as control. Results showed that the aqueous extract is more potent as compared to other extracts as it took less time to cause paralysis and death of the earthworms.
KEYWORDS: anthelmintic activity, Valeriana wallichi, Pheretima posthuma, piperazine citrate
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