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Wed, 02/11/2015 - 05:26  |  Anonymous
Published on:11th Feb, 2015
Indian Journal of Pharmaceutical Research and Education, 2011; 45(1):78-82
Pharmaceutical Education | doi:Nill

Synthesis and Biological Evaluation of Quinazolone Fused Schiff Bases


Authors and affiliation (s):

G. Mariappan , Saha B.P., Satyajit Dutta, Abhishek Majumder and Sudip Saha

Dept of Medicinal Chemistry, Himalayan Pharmacy Institute, Majhitar, Rangpo, E. Sikkim-737136

Abstract:

A new series of Quinazolone Schiff bases were synthesized. The structures of the synthesized compounds were confirmed on the basis of IR, 1HNMR. The synthesized compounds (X1 to X6) were screened for anti-inflammatory activity. Among the entire test compounds, X2 have shown promising activity as compared to the rest. All the experimental results were statistically significant.

KEYWORDS: Quinazolone, Anti-inflammatory, Schiff bases, Antibacterial, Antifungal.

 




 

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