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Published on:June 2018
Indian Journal of Pharmaceutical Education and Research, 2018; 52(4):550-557
Review Article | doi:10.5530/ijper.52.4.64

An Overview on the Insulin Preparations and Devices


Authors and affiliation (s):

Shery Jacob1*, Mohamed Aly Morsy2,3, Anroop Nair3

*1Department of Pharmaceutics, College of Pharmacy, Gulf Medical University, Ajman, UAE.

2Department of Pharmacology, Faculty of Medicine, Minia University, El-Minia, EGYPT.

3Department of Pharmaceutics, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, SAUDI ARABIA.

Abstract:

Insulin preparations are the mainstay in the management of type 1 along with various type 2 diabetes. Available insulin preparations are either short-acting or long-acting or mixture to mimic the physiological insulin secretion and their doses need to be individualized. Attempting to imitate normal secretion of insulin can be valuable paradigm for understanding and providing effective therapy. This review provides an outline about the composition, use, route of administration, injection site, pharmacokinetics, storage and handling of various insulin preparations. The efficacy and safety of various insulin preparations for the management of diabetes mellitus are discussed. In addition, the use and application of various insulin devices to improve adherence and provide optimum delivery are elaborated. Indeed, the patient awareness and adherence on these issues is crucial to achieve good glycemic control.

Key words: Short-acting insulin, Long-acting insulin, Mixture, Analogues, Handling, Devices, Diabetes.

 




 

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The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmaceutical Education and Research (IJPER) [ISSN-0019-5464] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 1967.

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