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Published on:September 2017
Indian Journal of Pharmaceutical Education and Research, 2017; 51(3s2):s363-s367
Original Article | doi:10.5530/ijper.51.3s.48

Investigation of Some Antibacterial and Antioxidant Properties of Wild Cirsium vulgare from Turkey

Authors and affiliation (s):

Temine Sabudak1, H. Hulya Orak*2, Dumrul Gulen3, Merve Ozer1, Hilmican Caliskan1, Ilayda Bahrisefit1, Evren Cabi4

1Department of Chemistry, Faculty of Science and Arts, Namik Kemal University, Tekirdag, TURKEY.

2Department of Food Technology, Vocational School of Technical Sciences, Namik Kemal Un., Tekirdag TURKEY.

3Department of Medical Microbiology School of Medicine, Namik Kemal University Tekirdag, TURKEY.

4Department of Biology,Faculty of Science and Arts, Namik Kemal University, Tekirdag, TURKEY.


Background: Cirsium vulgare (Savi) Ten; belongs the Asteraceae family and has common uses in some countries folk medicine. Objective: In this study, the determination of some antioxidant and antimicrobial properties of C. vulgare which is wild-grown from Turkey is aimed. Methods: Crude extracts of plants were obtained by using n-hexane, diethyl ether, ethyl acetate and methanol as solvent. Total phenolic content (TPC) and DPPH (2,2-diphenyl 2,2-diphenyl-1 picrylhydrazyl picrylhydrazyl) scavenging activity were determined in extracts. The antibacterial activity was tested against Staphylococcus aureus (ATCC 43300), Escherichia coli (ATCC 35218), Bacillus subtilis (NRRL NRS-744) and Pseudomonas aeruginosa (ATCC 27853). Results: The TPC and DPPH activities of extracts revealed significant differences by following sequence MeOH > diethyl ether > EtOAc > n-hexane. The highest inhibition effect of C. vulgare was found on P. aeruginosa. Conclusion: Results presented that C. vulgare can be researched for future investigations for isolations of biologically active compounds, where some of their characteristics are expected to be contribute to the natural compounds in pharmaceutical industry.

Key words: Cirsium vulgare, Phenolic content, DPPH activity, Antibacterial activity, P. aeruginosa.



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The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmaceutical Education and Research (IJPER) [ISSN-0019-5464] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 1967.


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