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Published on:July 2017
Indian Journal of Pharmaceutical Education and Research, 2017; 51(3s):s239-s243
Original Article | doi:10.5530/ijper.51.3s.21

Antimicrobial Activity and Chemical Composition Screening of Epilobium montanum Root


Authors and affiliation (s):

Kerem Canli1*, Ali Yetgin2, Ilgaz Akata3, Ergin Murat Altuner4

1Department of Biology, Faculty of Science, Dokuz Eylül University, Izmir, TURKEY

2Department of Biotechnology, Institute of Engineering and Science, Izmir Institute of Technology, Izmir, TURKEY

3Department of Biology, Faculty of Science, Ankara University, Ankara, TURKEY

4Department of Biology, Faculty of Science and Arts, Kastamonu University, Kastamonu, TURKEY

Abstract:

Medical herbs have many bioactive component and they are used in microbial treatment since ancient time. The resistance of pathogen to antibiotic is became a critical problem, so novel antimicrobial agent related research is required. Epilobium montanum related antimicrobial research doesn't exist, therefore root of this medicinal plant investigation was applied against 17 bacteria and 1 fungi by using disk diffusion method. These microbial species include Bacillus, Enterobacter, Enterococcus, Escherichia, Klebsiella, Listeria, Pseudomonas, Salmonella, Staphylococcus and Candida genera. Besides, chemical composition of this sample was determined by Gas Chromatography-Mass Spectroscopy. The results were presented that E. montanum has antimicrobial activity against all tested microbial species except E. coli. Seventeen major chemical components were determined, but some composition of this sample is not match with library. For this reason, this medicinal plant contain unknown molecules and this molecules should be analysed by NMR spectra for 3D structure determination and identification.

Key words: Epilobium montanum, Medicinal Plant, Antimicrobial Activity, Chemical Composition, Disk Diffusion Method, GC-MS.

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The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
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