Introduction: Novel Cu(II), Co(II) and Ni(II) complexes of 8-hydroxyquinolineazo analogues are synthesized from 5-((3-nitrophenyl)diazenyl) quinolin-8-ol (4a) and 5-((4-bromo-3- methylphenyl) diazenyl) quinolin-8-ol (4b). Methods: The structural environment and elemental composition of the synthesized metal complexes are confirmed by FT/IR, 1H NMR and CHNS/O elemental analyzer. The λ max and molecular mass are determined with the help of UV-visible and LC-MS spectrometer. Results: The magnetic susceptibility study suggested that the synthesized complexes are proposed with tetrahedral geometry. Among the six complexes, the bis bis 8, 8′ [5-((3-nitrophenyl) diazenyl) quinolinium] copper (4aLig2Cu) and bis 8, 8′ [5-((4-bromo-3-methylphenyl) diazenyl) quinolinium] copper (4bLig2Cu) showed significant antimicrobial activity. Conclusion: It was found that the metal complexes showed enhanced antimicrobial activity in comparison to their corresponding ligands.
Key words: Spectroscopic, Magnetic susceptibility, Antimicrobial, 8-Hydroxy quiniline, Antibiogram