Volume 61, Issue 1

Original Article(continued)

1. Development and Validation of New Analytical Technique for the Estimation of Vonoprazan Fumarate in Bulk Form and in Pharmaceutical Dosage Form

   Aishwarya Naik, Hiralben Mehta, Janki Thakkar

   pp. 423-428 · DOI: 10.5530/ijper.20273279 · 2026

   Background: Vonoprazan Fumarate is a used for Peptic ulcers and other acid-related diseases. Although several analytical methods are available, developing a simple, cost-effective, and environmentally friendly UV-visible…

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2. Clinical Efficacy and Safety of Centrally Procured Generic Tenofovir Alafenamide Fumarate: A Real-World Study

   Guoqin Zhu, Longchuan Zhu, Dan He

   pp. 429-438 · DOI: 10.5530/ijper.20275870 · 2026

   Objectives: This real-world study aimed to compare the early efficacy and safety of original versus generic Tenofovir Alafenamide Fumarate (TAF) in treating patients with Chronic Hepatitis B (CHB). Materials and Methods:…

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3. A Retrospective Analysis of Diabetic Ketoacidosis in Saudi Arabia: Incidence, Risk Factors, and Treatment Approaches

   Nawal Alsubaie, Lama Hani Sayed, Fatimah Mohammed Khudair, Salem Alsuwaidan, Najat Alghamdi, Faisal Almazroua, Khalid Manea Alotaibi, Amani Saleh Alrossies, Ammena Yahya Binsaleh, Badria Alotaibi, Nora Almosa, Ahmad Almalki, Aymen Alqurain, Prafulla Sabale

   pp. 439-447 · DOI: 10.5530/ijper.20272341 · 2026

   Aim/Background: Diabetic Ketoacidosis (DKA) is a life-threatening complication of diabetes mellitus that remains a major public health issue in Saudi Arabia, affecting patients with both type 1 and type 2 diabetes. This …

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4. Quantitative Benchmarking of Global Regulatory Frameworks for AI-Based Medical Devices: Innovation, Rigor and Emerging Trends

   Shivali Rahi, Perivellur Sadasivan Chandranand, Arpana Rana, Viney Lather

   pp. 448-456 · DOI: 10.5530/ijper.20273785 · 2026

   Objectives: Artificial Intelligence (AI)-based medical devices are expanding rapidly, yet their regulatory oversight remains fragmented across global agencies. Existing studies have largely been qualitative, emphasizing …

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5. A Study on Clinical Patterns and Outcomes of Acute Poisoning at a Tertiary Care Hospital

   Namana G, Sekhar Sharma, Raman Dang, Rakshitha NP

   pp. 457-463 · DOI: 10.5530/ijper.20275013 · 2026

   Background: Acute poisoning is a major global public health concern. Intentional and accidental exposure of a harmful substance. Depending on socioeconomic factors and accessibility of toxic substances, poisoning pattern…

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6. Realistic Bedside Consultation Based on Standardized Patients in Nursing Education: A Randomized Controlled Trial

   Huiwen Xu, Yinwen Ding, Zhie Gu, Shuang Qiu

   pp. 464-474 · DOI: 10.5530/ijper.20276972 · 2026

   Background: Consultation is the first step of health assessment, and it is an essential skill for nursing students. Clinical real patient practice was the best training method, but it is stressful and challenging for nur…

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7. Effects of Methotrexate on HIF-1α, HIF-2α and P4H-TM Expression in Breast Cancer Cells

   Orcun Can, Seyma Dumur, Abdulhalim Senyigit, Hafize Uzun, Dilek Duzgun Ergun, Berrin Papila, Cigdem Usul Afsar

   pp. 475-482 · DOI: 10.5530/ijper.20275981 · 2026

   Background: Methotrexate (MTX), a widely used antimetabolite, exhibits cytotoxic effects across multiple cancer types, yet its impact on hypoxia-related markers in Breast Cancer (BC) remains unclear. Purpose: This study …

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