Radical Scavenging and Antioxidant Activity of Ethanolic Extract of Mollugo nudicaulis by Invitro Assays

Abstract:

In the present study, the ability of scavenging free radicals of the ethanolic extract of Mollugo nudicaulis was determined by using 1,1-diphenyl- 2-picrylhydrazyl (DPPH), reducing power, ferric reducing antioxidant power (FRAP), hydroxyl radical scavenging assay, superoxide radical scavenging (SOD), hydrogen peroxide radical scavenging assay, nitric oxide scavenging assay (NO) and total antioxidant capacity assay. The results showed that the ethanolic extract of Mollugo nudicaulis has a significant antioxidant activity. The amount of flavonoids, tannin, phenol, carotene and lycopene were also determined. The extract has the high amount of phenolic content. Thus, the study suggests that Mollugo nudicaulis has a better source of natural antioxidants, which might be helpful in preventing the progress of oxidative stress.

Keywords: Free radical scavenging, antioxidant, Mollugo nudicaulis, oxidative stress.