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Published on:November 2019
Indian Journal of Pharmaceutical Education and Research, 2019; 53(4s):s487-s499
Review Article | doi:10.5530/ijper.53.4s.143

Difficulties Facing the Patients and Extra Burden for Healthcare Providers by Non-adherence to the Medications - A Comprehensive Review

Authors and affiliation (s):

Yahaya Hassan1,*, Ahmed Alaa Al-Temimi2, Rizwan Ramli3, Mohd Firdaus M. Saad3, Noorizan A. Aziz1

1Clinical Pharmacy Unit, School of Pharmacy, Management and Science University, Shah Alam, Selangor, MALAYSIA.

2Clinical Pharmacy Department, School of Pharmacy, Monash University Malaysia, Sunway, Selangor, MALAYSIA.

3Department Pharmacy Practice, Universiti Teknologi Mara, Puncak Alam, Selangor, MALAYSIA.


Background: Compliance is commonly and always being confused with concordance, which is a process by which a patient and health care provider make discussion and decisions together about treatment and their outcomes. General worldwide, noncompliance is a major obstacle and main challenges to the effective and efficient health care delivery. Estimation in 2003 by the World Health Organization indicates that only approximately 50% of chronic diseases patients that us living in developed countries follow their treatment as scheduled and recommended by clinicians. Objectives: To report on the status and future trends of Medications adherence Materials: Published journal article and conference reports. Method: Data Extraction, data on area related to the patients and healthcare providers for non-adherence to the Medications were gleaned from various publications. Results and Conclusion: Low compliance to prescribed medical is a complex problem, especially for patients with a chronic illness. With increasing numbers of medications shown to do better than harm when taken as prescribed, low compliance is a growing concern, seriously undermining the benefits of current medical care. Medical non-compliance has been identified as a major public health problem that imposes a considerable financial burden upon modern health care systems.

Key words: Non-adherence, Quality in health care, Patient burden, Drug Compliance, Comprehensive.



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The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmaceutical Education and Research (IJPER) [ISSN-0019-5464] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 1967.


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